For pharma & biotech, purification is often the crucial step of downstream processing. As high purities are required for APIs, process development teams have to limit the impact on yield / recovery, productivity and solvent consumption. In early development stages, optimizing the process is a race for time-to-market.
Thanks to Inexiotech intensification technology, we help our clients reach an optimal purification method faster and enable an early start of phase 1 clinical trials. That advantage is clear in particular for difficult separations or where the yield is the main cost driver.
For APIs that are already in production, if the demand increases but the purification plant is at maximum capacity, Inexiotech can overcome the issue by providing a drastic improvement of the separation performance with minimal changes to the process. This enables to increase the capacity minor changes to the equipment and no changes to the stationary and mobile phases implemented.